AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |
Back to Blog
Kid3 cardiomyocyte3/14/2023 Ganapathy B, Polizzotti BD, Bennett D, Nandhagopal N, Kühn B. Neuregulin-1 administration protocols sufficient for stimulating cardiac regeneration in young mice do not induce somatic, organ, or neoplastic growth. PLoS One 2016 11(5): e0155456, PMID: 27175488, PMCID: PMC4866786 Missinato M, Saydmohammed M, Zuppo DA, Rao KS, Opie GW, Kühn B, Tsang M. Dusp6 attenuates Ras/MAPK signaling to limit zebrafish heart regeneration. Development 2018 145(5): dev157206. Gong Z, Tasset I, Diaz A, Anguiano J, Tas E, Cui L, Kuliawat R, Liu H, Kühn B, Cuervo AM, Muzumdar R. Humanin is an endogenous activator of chaperone- mediated autophagy. J Cell Biol 2018 217(1): 635–647. Control of cytokinesis by β-adrenergic receptors indicates an approach for regulating cardiomyocyte endowment. Sci. Transl. Med. Liu H, Zhang C-H, Ammanamanchi N, Suresh S, Lewarchik C, Rao K, Uys GM, Han L, Abrial M, Yimlamai D, Ganapathy B, Guillermier C, Chen N, Khaladkar M, Spaethling J, Eberwine JH, Kim J, Walsh S, Choudhury S, Little K, Francis K, Sharma M, Viegas M, Bais A, Kostka D, Ding J, Bar-Joseph Z, Wu Y, Yechoor V, Moulik M, Johnson J, Weinberg J, Reyes-Múgica M, Steinhauser ML and Kühn B. Han L, Choudhury S, Mich-Basso JD, Ammanamanchi N, Ganapathy G, Suresh S, Khaladkar M, Singh J, Maehr R, Zuppo DA, Kim J, Eberwine JH, Wyman SK, Wu Y & Kühn B. Lamin B2 levels regulate polyploidization of cardiomyocyte nuclei and myocardial regeneration. Dev. β-adrenergic receptor activity mediates between contraction and proliferation in heart muscle cells. Suppression of contractions in cycling cardiomyocytes is mediated by altered β-adrenergic receptor signaling. Revised manuscript in preparation for resubmission Liu H, Lewarchik CM, Ammanamanchi N, Rao K, Mich-Basso JD, Stolz DB, Sullivan ML, Mistry S, Kellam B, Wu Y, Gotthardt M, Salama G, Kühn B. Post-doctoral Research Fellow, Boston Children's Hospital/Harvard Medical School, 2004-2005 Resident Physician, Yale-New Haven Hospital, 1999-2002Ĭlinical Fellow, Boston Children's Hospital/Harvard Medical School, 2002-2007 American Society for Clinical Investigation, 2016-Present.American Association for the Advancement of Science, 2007-Present.American Heart Association, 2004-Present.American College of Cardiology, 2002-Present.American Academy of Pediatrics, 1999-2008.Professional and Scientific Society Memberships He and his team of researchers are focused on discovering ways to make cardiomyocytes replicate and proliferate, so as to enable the heart to heal itself in cases of heart failure or congenital defects.Ī pioneer in this area of study, Kühn is the recipient of numerous grants and awards, including the American College of Cardiology's prestigious Young Investigator Award, the Basil O'Connor Award from the March of Dimes Birth Defects Foundation, and Scientist Development Grant from the American Heart Association, to name a few. Understanding the unique workings of heart muscle cells - cardiomyocytes - is the passion of physician-scientist Bernhard Kühn.
0 Comments
Read More
Leave a Reply. |